Aseem Ansari

Aseem Ansari

Biochemistry

Studying the regulation of gene expression at the interface of chemistry biology and genomics, dissecting genome-wide transcriptional cascades.

Fotis Asimakopoulous

Fotis Asimakopoulous

Medicine

Genomic approaches to characterize multiple myeloma.

Alan Attie

Alan Attie

Biochemistry

Molecular genetics of diabetes & insulin resistance; cell biology of lipoprotein assembly and cholesterol trafficking.

David Beebe

David Beebe

Biomedical Engineering

Design, fabrication, and testing of novel micro fabrication techniques; microdevices and microsystems designed to facilitate advances in biology.

Emery Bresnick

Emery Bresnick

Cell & Regenerative Biology

Multidisciplinary approaches to understand stem/progenitor cell function, blood cell development, and vascular biology.

Mark Burkard

Mark Burkard

Medicine, Hematology-Oncology

Identification of genetic alterations in cancer cells; cancer genomics; targeted treatment strategies for breast cancer.

Karl Broman

Karl Broman

Biostatistics and Medical Informatics

Statistical problems in genetics, genomics and molecular biology. Development of improved methods for detecting and identifying genes contributing to variation in complex traits.

Joshua Coon

Joshua Coon

Chemistry

Development and application of new technologies and instrumentation for automated, large-scale whole protein characterization.

Mark Craven

Mark Craven

Biostatistics and Medical Informatics

Development and application of machine-learning methods to inferring models of, and reasoning about, networks of interactions among genes, proteins, clinmical and environmental factors, and phenotypes of interest.

Colin Dewey

Colin Dewey

Biostatistics & Medical Informatics

Algorithms and statistical models for genomics.

Timothy Donohue

Timothy Donohue

Bacteriology

Studying synthesis and activity of proteins that function in critical energy generating pathways in Rhodobacter sphaeroides.

Corinne Engelman

Corinne Engelman

Population Health Sciences

Genetic epidemiology of Alzheimer’s Disease and Vitamin D deficiency.

Catherine Fox

Catherine Fox

Biomolecular Chemistry

Genomic and computational analyses of chromsome replication in eukaryotes.

Audrey Gasch

Audrey Gasch

Genetics

The genomics of yeast responses to environmental stress and starvation.

Anthony Gitter

Anthony Gitter

Morgridge Inst. for Research; Biostat. & Med. Informatics

Development of computational approaches to reconstruct signally pathways and transcriptional regulatory networks from multiple types of high throughput data.

Michael Gould

Michael Gould

Oncology

Molecular genetics of mammary carcinogenesis and translation research in the area of breast cancer prevention and therapy.

Jo Handelsman

Jo Handelsman

Wisconsin Institute for Discovery

Understanding diversity in microbial communities and their role in infectious disease.

Melissa Harrison

Melissa Harrison

Biomolecular Chemistry

Understanding of how information encoded in the genome is differentially interpreted during organismal development.

Chris Hittinger

Chris Hittinger

Genetics

Diversity and evolution of yeast carbon metabolism networks.

Christina M. Hull

Christina M. Hull

Biomolecular Chemistry

Molecular biology of human fungal pathogens.

Christina Kendziorski

Christina Kendziorski

Biostatistics and Medical Informatics

Development and application of statistical methods for gene mapping and gene expression array studies.

Pamela Kreeger

Pamela Kreeger

Biomedical Engineering

Systems biology, ovarian cancer, endocrine signaling.

Peter Lewis

Peter Lewis

Biomolecular Chemistry; WID

Chromatin dynamics influence on gene expression during mammalian development and tumorigenesis.

Laurence Loewe

Laurence Loewe

Genetics

Evolutionary systems biology, evolutionary genetics, species extinction, antibiotics resistance evolution, population genetics, systems biology, simulation, parameter estimation, distributed computing.

Megan McClean

Megan McClean

Biomedical Engineering

Biological signal processing: signal specificity; determination of in vivo kinetics; transcription factor regulation; controllability.

John Markley

John Markley

Biochemistry

NMR spectroscopy and its biological applications; structure function relationships in proteins; and stable-isotope assisted multinuclear NMR.

Michael Newton

Michael Newton

Biostatistics and Medical Informatics

Developing statistical methods to address problems with the comparison of expression arrays.

C. David Page

C. David Page

Biostatistics and Medical Informatics

Data mining and machine learning, with applications to bioinformatics, chemoinformatics, and health sciences; inductive learning programming.

David Pagliarini

David Pagliarini

Biochemistry

Investigation of the biochemical underpinnings of mitochondrial dysfunction in human diseases.

Sean Palecek

Sean Palecek

Chemical and Biological Engineering

Cellular engineering, intracellular signal transduction, cell and protein biosensors.

Bret Payseur

Bret Payseur

Genetics

Population genetic processes that determine patterns and levels of variation throughout the genome, including natural selection, recombination, and mutations.

Caitlin Pepperell

Caitlin Pepperell

Medical Microbiology & Immunology; Medicine

Force that shape evolution of human pahogens; influence of infection diseases on human evolution; effect of environment on population level patterns of infectious disease.

Nicole Perna

Nicole Perna

Genetics

Genome scale comparative analysis to identify the genetic elements that distinguish one complete genome from another.

Brian Pfleger

Brian Pfleger

Chemical and Biological Engineering

Synthetic biology, metabolic engineering, biotechnology, protein engineering, natural products.

John Pool

John Pool

Genetics

New inference methods for population genomic sequence data; genetic basis of parallel melanic evolution in Drosophila.

Srivatsan Raman

Srivatsan Raman

Biochemistry

Systems and synthetic biology approach to understanding and designing biology at multiple scales - proteins, microbial pathways and microbiota.

Parmesh Ramanathan

Parmesh Ramanathan

Electrical & Computer Engineering

Characterization of the temporal dynamics of networks of gene interactions; longer-term goal, creation of a virtual foundry for genomic circuits.

Jennifer Reed

Jennifer Reed

Chemical and Biological Engineering

Systems biology, metabolic model development and analysis, metabolic engineering, biofuels, bioremediation, and biotechnology.

Federico Rey

Federico Rey

Bacteriology

Gut bacterial metabolism and human health; microbial cross-feeding.

Sushmita Roy

Sushmita Roy

Biostatistics & Medical Informatics

Inference of structure and function of regulatory networks; Comparative analysis of expression modules across species.

Kris Saha

Kris Saha

Biomedical Engineering

Use of human stem cells together with emerging engineering methods in material science and synthetic biology to model human disease and advance personalized medicine.

David C. Schwartz

David C. Schwartz

GSTP Program Director
Chemistry / Genetics

Chemistry and biology of single molecule systems with applications to genomic sciences.

Eric Shusta

Eric Shusta

Chemical and Biological Engineering

Development of an in vitro model of the Blood Brain Barrier (BBB);analysis of membrane proteome of the BBB.

Ahna Skop

Ahna Skop

Genetics

Cytokinesis and cell cycle proteomics.

Rupa Sridharan

Rupa Sridharan

Cell and Regenerative Biology

Stem cell epigenetic. Defining how the epigenome controls pluripotency.

Lloyd Smith

Lloyd Smith

Chemistry

Development and application of novel methods and approaches for the analysis and manipulation of biomolecules.

Rupa Sridharan

Rupa Sridharan

Cell & Regenerative Biology

Epigenetics of cell fate change.

Garret Suen

Garret Suen

Bacteriology

Rumen microbiology; herbivore-associated microbial ecology; metagenomics; biofuels.

Michael Sussman

Michael Sussman

Biochemistry

Signal transduction in eukaryotes, development of genomic technologies, plasma membrane receptors and ion transporters, Arabidopsis thaliana.

James Thomson

James Thomson

Anatomy

The biology of pluripotency. Understanding how human embryonic stem (ES) cells choose between self-renewal, apoptosis, and differentiation into specific lineages.

Ophelia Venturelli

Ophelia Venturelli

Biochemistry

Evolutionary design principles of biomolecular networks and ecologies and engineering of feedback control systems.

Grace Wahba

Grace Wahba

Statistics

Development, testing and application of new methods for multivariate function estimation and statistical model building.

Brian Yandell

Brian Yandell

Statistics

Statistical genomics; theoretical statistics; applications in selected areas of agriculture.

John Yin

John Yin

Chemical and Biological Engineering

Developing experimental and theoretical approaches to study growth, adaptation, and inactivation of viruses.